UT Transplant Center Faculty
Daniel J. Riley, MD
1987, MD, State University of New York Health Science Center at Syracuse, Syracuse, NY
1996, Postdoctoral Fellowship, Molecular Medicine, UTHSCSA, San Antonio, TX
1993, Clinical Fellowship, Nephrology, UTHSCSA, San Antonio, TX
1990, Residency, Internal Medicine, Case Western Reserve University/University Hospitals of Cleveland, Cleveland, OH
Research interests: Molecular and cellular basis of polycystic kidney disease; mechanisms and implications of DNA damage repair and genomic instability; tumor suppressor genes, control of the cell division cycle and apoptosis, basic mechanisms of cellular growth, hypertrophy, and proliferation; protein kinases; gene therapy; clinical kidney transplantation outcomes and complications; glomerular mesangial cell biology, cellular hypertrophy in glomerulonephritis and diabetic nephropathy.
Clinical interests: Polycystic kidney disease, kidney transplantation, nephrology
Chen Y, Craigen WJ, Riley DJ. Nek1 regulates cell death and mitochondrial membrane permeability through phosphorylation of VDAC1. (Feature article) Cell Cycle 2009 Feb;8:257-267.
Pollack MS, Werner SL, Riley DJ. Case Report: A donor-specific anti-DP antibody apparently causing acute antibody-mediated rejection in a kidney re-transplant recipient In: Visuals of the Clinical Histocompatibility Workshop, One Lambda, Inc., Canoga Park, CA 2009 Jan;:62-64.
Chen Y, Chen PL, Chen CF, Jiang XZ, Riley DJ. Never-in-mitosis related kinase 1 functions in DNA damage response and checkpoint control. (Feature article) Cell Cycle 2008 Oct;7:3194-3201.
Das F, Ghosh-Choudhury N, Mahimainathan L, Venkatesan B, Feliers D, Riley DJ, Kasinath BS, Choudhury GG. Raptor-rictor axis in TGFbeta-induced protein synthesis Cell Signal 2008 Feb;20:409-423.
Habib SL, Riley DJ, Mahimainathan L, Bhandari B, Choudhury GG, Abboud HE. Tuberin regulates the DNA repair enzyme OGG1 Am J Physiol Renal Physiol 2008 Jan;294:281-290.
Wagner B*, Ricono JM*, Gorin Y, Block K, Arar MY, Riley D, Choudhury GG, Abboud HE. *Equally contributing authors. Mitogenic signaling via platelet-derived growth factor beta in metanephric mesenchymal cells J Am Soc Nephrol 2007 Nov;18(11):2903-2911.
Cotant C, Okulicz JF, Brezina B, Riley DJ, Conger NG. Human monocytic ehrlichiosis in a renal transplant patient Scand J Infect Dis 2006 Jan;38:699-702.
Chen Y, Chiang HC, Litchfield PL, Pena M, Riley DJ. Nek1-deficient Kat2J mice develop Cysts from multiple different tubular types; 2008 Jan. (J Am Soc Nephrol; vol. 19).
Gakunga PT, Horn D, Rugh JD, Riley DJ, Chen Y, Abboud SL. Nek 1 deficiency in Mice Impairs Cranial Base Synchondrosis Growth; 2007 Jan. (American Association of Dental Research Annual Meeting Program Book).
Lewis C, Gluhak-Heinrich J, Feng J, Horn D, Woodruff K, Cardenas LM, Riley DJ, Chen Y, Macdougall MJ, Abboud SL. Nek 1 protein kinase deficiency in kat2J mice alters odontogenesis; 2007 Jan. (American Association of Dental Research Annual Meeting Program Book).
Biosketch: Dr. Daniel Riley received his medical degree at S.U.N.Y. Health Science Center at Syracuse. He completed his internship and residency at Case Western Reserve University/University Hospitals of Cleveland, Cleveland, Ohio and a fellowship in Nephrology at The UT Health Science Center at San Antonio. In addition to running an active research laboratory, he assists in the pre- and post-operative care of kidney and pancreas transplant patients.