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UT Transplant Center Faculty

Daniel J. Riley, MD

Associate Professor

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Board Certifications:

1987, MD, State University of New York Health Science Center at Syracuse, Syracuse, NY

Postgraduate training:
1996, Postdoctoral Fellowship, Molecular Medicine, UTHSCSA, San Antonio, TX
1993, Clinical Fellowship, Nephrology, UTHSCSA, San Antonio, TX
1990, Residency, Internal Medicine, Case Western Reserve University/University Hospitals of Cleveland, Cleveland, OH

Research interests: Molecular and cellular basis of polycystic kidney disease; mechanisms and implications of DNA damage repair and genomic instability; tumor suppressor genes, control of the cell division cycle and apoptosis, basic mechanisms of cellular growth, hypertrophy, and proliferation; protein kinases; gene therapy; clinical kidney transplantation outcomes and complications; glomerular mesangial cell biology, cellular hypertrophy in glomerulonephritis and diabetic nephropathy.

Clinical interests: Polycystic kidney disease, kidney transplantation, nephrology

Chen Y, Craigen WJ, Riley DJ. Nek1 regulates cell death and mitochondrial membrane permeability through phosphorylation of VDAC1. (Feature article) Cell Cycle 2009 Feb;8:257-267.

Pollack MS, Werner SL, Riley DJ. Case Report: A donor-specific anti-DP antibody apparently causing acute antibody-mediated rejection in a kidney re-transplant recipient In: Visuals of the Clinical Histocompatibility Workshop, One Lambda, Inc., Canoga Park, CA 2009 Jan;:62-64.

Chen Y, Chen PL, Chen CF, Jiang XZ, Riley DJ. Never-in-mitosis related kinase 1 functions in DNA damage response and checkpoint control. (Feature article) Cell Cycle 2008 Oct;7:3194-3201.

Das F, Ghosh-Choudhury N, Mahimainathan L, Venkatesan B, Feliers D, Riley DJ, Kasinath BS, Choudhury GG. Raptor-rictor axis in TGFbeta-induced protein synthesis Cell Signal 2008 Feb;20:409-423.

Habib SL, Riley DJ, Mahimainathan L, Bhandari B, Choudhury GG, Abboud HE. Tuberin regulates the DNA repair enzyme OGG1 Am J Physiol Renal Physiol 2008 Jan;294:281-290.

Wagner B*, Ricono JM*, Gorin Y, Block K, Arar MY, Riley D, Choudhury GG, Abboud HE. *Equally contributing authors. Mitogenic signaling via platelet-derived growth factor beta in metanephric mesenchymal cells J Am Soc Nephrol 2007 Nov;18(11):2903-2911.

Cotant C, Okulicz JF, Brezina B, Riley DJ, Conger NG. Human monocytic ehrlichiosis in a renal transplant patient Scand J Infect Dis 2006 Jan;38:699-702.

Chen Y, Chiang HC, Litchfield PL, Pena M, Riley DJ. Nek1-deficient Kat2J mice develop Cysts from multiple different tubular types; 2008 Jan. (J Am Soc Nephrol; vol. 19).

Gakunga PT, Horn D, Rugh JD, Riley DJ, Chen Y, Abboud SL. Nek 1 deficiency in Mice Impairs Cranial Base Synchondrosis Growth; 2007 Jan. (American Association of Dental Research Annual Meeting Program Book).

Lewis C, Gluhak-Heinrich J, Feng J, Horn D, Woodruff K, Cardenas LM, Riley DJ, Chen Y, Macdougall MJ, Abboud SL. Nek 1 protein kinase deficiency in kat2J mice alters odontogenesis; 2007 Jan. (American Association of Dental Research Annual Meeting Program Book).

Biosketch: Dr. Daniel Riley received his medical degree at S.U.N.Y. Health Science Center at Syracuse. He completed his internship and residency at Case Western Reserve University/University Hospitals of Cleveland, Cleveland, Ohio and a fellowship in Nephrology at The UT Health Science Center at San Antonio. In addition to running an active research laboratory, he assists in the pre- and post-operative care of kidney and pancreas transplant patients.

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